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Insulin Polyclonal Antibody

CAT: 0763-E-AB-70202-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-70202-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
Abbreviation
Insulin
UniProt
P01325
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant protein corresponding to Mouse insulin
Target
IDDM; IDDM1; IDDM2; ILPR; ins; INS; Insulin A chain; Insulin B chain; IRDN; MODY10; Preproinsulin; Proinsulin; Proinsulin precursor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Affinity purification
Concentration
300 μg/mL
Dilution
IHC 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.nature.com/articles/s41598-020-57486-w
Isotype
IgG
Product Datasheet
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