ITGAV Polyclonal Antibody

• Background :

  The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

• Abbreviation :

  ITGAV

• UniProt :

  P06756, P43406

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V

• Target :

  Antigen identified by monoclonal L230; CD 51; CD51; DKFZp686A08142; Integrin alpha five; integrin alpha V beta 3; Integrin alpha-5; integrin alpha-V; Integrin alpha-V light chain; integrin alphaVbeta3; integrin; alpha V (vitronectin receptor; alpha polypeptide; antigen CD51) ; ITAV; ITGAV; MSK 8; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Cardiovascular; Microbiology; Stem Cells

• Purification :

  Affinity purification

• Concentration :

  0.76 mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  116kDa

• Observed Molecular Weight :

  130kDa

• Isotype :

  IgG