ITGA2 Polyclonal Antibody

• Background :

  This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

• Abbreviation :

  ITGA2

• UniProt :

  P17301

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human ITGA2

• Target :

  BR; CD 49b; CD49 antigen like family member B; CD49 antigen-like family member B; CD49b; CD49b antigen; Collagen receptor; DX5; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency; included; GPIa; HPA 5 included; HPA5 included; Human platelet alloantigen system 5; Integrin alpha 2; Integrin alpha II; Integrin alpha-2; Integrin; alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) ; ITA2; ITGA2; Platelet alloantigen Br (a) ; included; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/IIa; Platelet membrane glycoprotein Ia; Platelet receptor for collagen; deficiency of; included; Very late activation protein 2 receptor alpha 2 subunit; VLA 2 alpha chain; VLA 2; VLA 2 subunit alpha; VLA-2 subunit alpha; VLA2; VLA2 receptor alpha 2 subunit; VLAA2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Metabolism; Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.4 mg/mL

• Dilution :

  WB 1:200-1:1000; IHC 1:25-1:100

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  129kDa

• Citation 01 :

  https://journals.sagepub.com/doi/abs/10.1177/1535370218791797

• Isotype :

  IgG