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Survivin Polyclonal Antibody

CAT: 0763-E-AB-68318-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-68318-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Abbreviation
Survivin
UniProt
O15392
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human Survivin
Target
API4; EPR-1; BIRC5; Survivin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Neuroscience
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
8kDa/13kDa/15kDa/16kDa/18kDa
Observed Molecular Weight
16KDa
Isotype
IgG

UniProtKB · O15392

Baculoviral IAP repeat-containing protein 5

BIRC5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15392
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BIRC5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A2SUH6, B2R4R1, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCell cycleCell divisionChromosome partitionHost-virus interactionMitosisTranscriptionTranscription regulation

Cellular component

CentromereChromosomeCytoplasmCytoskeletonKinetochoreMicrotubuleNucleus

Ligand

Metal-bindingZinc

Molecular function

Protease inhibitorRepressorThiol protease inhibitor

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Alternative Products

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JOT-AP01683-01Survivin Polyclonal Antibody
APR06263GPolyclonal Survivin Antibody
20-1091-50Polyclonal antibody to Survivin

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