PDGFR beta Polyclonal Antibody

• Background:

  This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

• Abbreviation:

  PDGFR beta

• UniProt:

  P09619

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant fusion protein of human PDGFR beta (NP_002600.1) .

• Target:

  CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT; PDGF Receptor beta; PDGFRB; PDGFR beta

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF

• Field of Research:

  Cancer; Cardiovascular; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  IHC 1:50-1:200; IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG