PDGFR beta Polyclonal Antibody

CAT: 0763-E-AB-67422-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0763-E-AB-67422-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Abbreviation
PDGFR beta
UniProt
P09619
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human PDGFR beta (NP_002600.1) .
Target
CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT; PDGF Receptor beta; PDGFRB; PDGFR beta
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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