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LTF Polyclonal Antibody

CAT: 0763-E-AB-65979-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-65979-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
LTF
UniProt
P02788
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human LTF (NP_002334.2) .
Target
LTF; GIG12; HEL110; HLF2; LF
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.mdpi.com/1403090
Isotype
IgG

UniProtKB · P02788

Lactotransferrin

TRFL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02788
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LTF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Lactoferrin
EC number
3.4.21.-
Processing
Precursor
Secondary accessions
A8K9U8, B2MV13, B7Z4X2, E7EQH5, O00756, Q16780, Q16785, Q16786, Q16789, Q5DSM0, Q8IU92, Q8IZH6, Q8TCD2, Q96KZ4, Q96KZ5, Q9H1Z3, Q9UCY5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usage

Molecular function

AntibioticAntimicrobialDNA-bindingHeparin-bindingHydrolaseProteaseSerine protease

Cellular component

CytoplasmNucleusSecreted

PTM

Disulfide bondGlycoproteinIsopeptide bondUbl conjugation

Biological process

ImmunityIon transportIron transportOsteogenesisTranscriptionTranscription regulationTransport

Ligand

IronMetal-binding

Domain

RepeatSignal

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