CD27 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

• Abbreviation :

  CD27

• UniProt :

  P26842

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Recombinant fusion protein of human CD27 (NP_001233.1) .

• Target :

  CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC; IF

• Field of Research :

  Cancer; Immunology; Stem Cells

• Purification :

  Affinity purification

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:50-1:200; IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG