MEF2D Polyclonal Antibody

CAT: 763-E-AB-53508-01Size: 20 µLDry Ice: NoHazardous: No
20 µLSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. MEF2D (Myocyte Enhancer Factor 2D) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Development Angiotensin activation of ERK. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MEF2A.
Abbreviation
MEF2D
UniProt
Q14814
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human MEF2D
Target
DKFZp686I1536; MADS box transcription factor 2 polypeptide D; Mef2d; MEF2D; Myocyte enhancer factor 2D; Myocyte specific enhancer factor 2; polypeptide D; Myocyte specific enhancer factor 2D; Myocyte-specific enhancer factor 2D
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Neuroscience
Purification
Antigen affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:35-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG