GRIA4 Polyclonal Antibody

CAT: 0763-E-AB-53406-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-53406-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Abbreviation
GRIA4
UniProt
P48058
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human GRIA4
Target
AMPA 4; AMPA selective glutamate receptor 4; AMPA-selective glutamate receptor 4; AMPA4; GluA 4; GluA4; GluR 4; GluR D; GluR-4; GluR-D; GluR4; GLUR4C; GLURD; Glutamate receptor 4; Glutamate receptor ionotrophic AMPA 4; Glutamate receptor ionotropic; GRIA 4; Gria4; GRIA4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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