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TBX1 Polyclonal Antibody

CAT: 0763-E-AB-53339-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-53339-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS) /velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Abbreviation
TBX1
UniProt
O43435
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human TBX1
Target
Brachyury; CAFS; CTHM; DGCR; DGS; DORV; T box; T box 1; T box 1 transcription factor; T box 1 transcription factor C; T box protein 1; T box transcription factor TBX 1; T box transcription factor TBX1; T-box protein 1; T-box transcription factor TBX1; TBX 1; TBX 1C; tbx1; TBX1; TBX1C; Testis specific T box protein; Testis-specific T-box protein; TGA; VCFS
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience
Purification
Antigen affinity purification
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

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