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HMGCLL1 Polyclonal Antibody

CAT: 0763-E-AB-52900-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52900-01Size:20 µL
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Background
Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S) -3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Abbreviation
HMGCLL1
UniProt
Q8TB92
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human HMGCLL1
Target
3 hydroxymethyl 3 methylglutaryl CoA lyase like 1;3 hydroxymethyl 3 methylglutaryl CoA lyase like protein 1;3 hydroxymethyl 3 methylglutaryl CoA lyase; cytoplasmic;3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase like 1; bA418P12.1; Endoplasmic reticulum 3 hydroxymethyl 3 methylglutaryl CoA lyase; er cHL; Probable 3 hydroxymethyl 3 methylglutaryl CoA lyase 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Metabolism; Signal transduction
Purification
Antigen affinity purification
Concentration
1.26 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q8TB92

3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic

HMGC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TB92
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HMGCLL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.1.3.4
Processing
—
Secondary accessions
B1AQ42, B3KNV0, B7Z1S7, F8W793, Q6ZSA9
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulumMembrane

Biological process

Lipid metabolism

PTM

LipoproteinMyristate

Molecular function

Lyase

Ligand

Metal-binding

Technical term

Proteomics identificationReference proteome

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