PPP1R3C Polyclonal Antibody

• Background:

  This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.

• Abbreviation:

  PPP1R3C

• UniProt:

  Q9UQK1

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human PPP1R3C

• Target:

  OTTHUMP00000020089; Phosphatase 1; regulatory inhibitor subunit 5; PP1 subunit R5; ppp1r3c; PPP1R5 ; PPR3C; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; protein phosphatase 1; regulatory (inhibitor) subunit 3C; Protein targeting to glycogen; PTG; R5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Metabolism; Signal transduction

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG