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PPP1R13L Polyclonal Antibody

CAT: 0763-E-AB-15724-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15724-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
Abbreviation
PPP1R13L
UniProt
Q8WUF5
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human PPP1R13L
Target
IASPP; inhibitor of apoptosis stimulating protein of p53; Inhibitor of ASPP protein; NFkB interacting protein 1; NKIP1; PPP1R13B-like protein; PPP1R13L; Protein iASPP; protein phosphatase 1 regulatory (inhibitor) subunit 13 like; RAI; RelA-associated inhibitor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
89kDa
Isotype
IgG

UniProtKB · Q8WUF5

RelA-associated inhibitor

IASPP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WUF5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PPP1R13L
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Domain

ANK repeatRepeatSH3 domain

Biological process

ApoptosisTranscriptionTranscription regulation

Disease

CardiomyopathyDisease variantEctodermal dysplasia

Cellular component

CytoplasmNucleus

Molecular function

Repressor

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