PDCD4 Polyclonal Antibody

• Background:

  Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.

• Abbreviation:

  PDCD4

• UniProt:

  Q53EL6

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human PDCD4

• Target:

  Death up-regulated gene protein; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor; Neoplastic transformation inhibitor protein; Nuclear antigen H731; Nuclear antigen H731 like; Nuclear antigen H731 like protein; Nuclear antigen H731-like; PDCD 4; Pdcd4; PDCD4; Programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor) ; Programmed cell death protein 4; Protein 197/15a; Protein MA-3; Tis; Topoisomerase-inhibitor suppressed protein

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Epigenetics and Nuclear Signaling

• Purification:

  Antigen affinity purification

• Concentration:

  0.6 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:40-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG