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ICAM-1 Polyclonal Antibody

CAT: 0763-E-AB-40590-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-40590-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Abbreviation
ICAM-1
UniProt
Q00238
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant Rat ICAM-1 protein expressed by E.coli.
Target
Icam1; intercellular adhesion molecule 1; CD54
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology; Microbiology; Cardiovascular; Stem Cells; Immunology ; Cardiovascular; Neuroscience
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57kDa
Observed Molecular Weight
110kDa
Isotype
IgG

UniProtKB · Q00238

Intercellular adhesion molecule 1

ICAM1_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
Q00238
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Icam1
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
ICAM-1, RICAM-I
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Technical term

Reference proteome
Product Datasheet
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