Angiotensinogen Polyclonal Antibody

CAT: 0763-E-AB-40478-01Size: 25 µLDry Ice: NoHazardous: No

1 / 3

CAT#:0763-E-AB-40478-01Size:25 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Abbreviation

Angiotensinogen

UniProt

P11859

Host

Rabbit

Reactivity

Mouse; Rat

Immunogen

Recombinant Mouse Angiotensinogen protein

Target

Aangiotensinogen (serpin peptidase inhibitor clade A member 8) ; AGT; AI265500; Alpha 1 antiproteinase antitrypsin; Ang; Ang I; Ang II; Ang III; AngII; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-3; Angiotensinogen (PAT) ; Angiotensinogen; ANGT; ANHU; ANRT; AT-2; AT-II; Des-Asp[1]-angiotensin II; PAT; Pre angiotensinogen; Serine (or cysteine) proteinase inhibitor; Serpin A8; Serpin peptidase inhibitor clade A member 8; SERPINA8

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Signal Transduction

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:2000-1:5000; IHC 1:100-1:300

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

52 kDa

Observed Molecular Weight

52 kDa

Isotype

IgG

UniProtKB · P11859

Angiotensinogen

ANGT_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: P11859
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Agt
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Technical term

3D-structureReference proteome

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

Molecular function

VasoactiveVasoconstrictor

Related Products

Catalog	Name
E-PP-0695-01	Angiotensinogen (1-13)
AN300511P	Recombinant Angiotensinogen/AGT Monoclonal Antibody
E-PP-0698-01	Angiotensinogen (1-14), Rat
AN300214P	Recombinant Angiotensinogen/SerpinA8/AGT Monoclonal Antibody
AN300213P	Recombinant SerpinA8/Angiotensinogen/AGT Monoclonal Antibody
E-PP-0696-01	Angiotensinogen (1-14), human
E-PP-0697-01	Angiotensinogen (1-14), Porcine
E-CL-R0138-01	Rat AGT (Angiotensinogen) CLIA Kit
E-PP-0548-01	Ac-Angiotensinogen (1-14), human
E-PP-0549-01	Ac-Angiotensinogen (1-14), porcine

Alternative Products

Catalog	Name
bs-20778R-01	Angiotensinogen Polyclonal Antibody
TRV-012356-01	Polyclonal Antibody to Angiotensinogen (AGT)
CAU27113-01	Angiotensinogen (AGT) Polyclonal Antibody
GTR18306669	Angiotensinogen Rabbit Polyclonal Antibody
GTR17721680-01	Angiotensinogen Mouse Polyclonal Antibody
TMAB-02556-01	Anti-Angiotensinogen Polyclonal Antibody