EIF4EBP1 Polyclonal Antibody

• Background:

  Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

• Abbreviation:

  EIF4EBP1

• UniProt:

  Q13541

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein

• Target:

  4E-BP1;4EBP1;4EBP1; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; Eif4ebp1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Metabolism

• Purification:

  Antigen Affinity Purification

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-1:400

• Buffer:

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG