HDAC5 Polyclonal Antibody

• Background:

  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

• Abbreviation:

  HDAC5

• UniProt:

  Q9UQL6

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of Ser498.

• Target:

  Antigen NY CO 9; Antigen NY-CO-9; HD5; HDAC 5; HDAC5; HDAC5; Histone deacetylase 5; NY CO 9

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-p; IF

• Field of Research:

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  122kDa

• Observed Molecular Weight:

  122kDa

• Isotype:

  IgG