HDAC8 Polyclonal Antibody

• Background :

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.

• Abbreviation :

  HDAC8

• UniProt :

  Q9BY41

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Recombinant protein of human HDAC8

• Target :

  CDA07; CDLS5; HD 8; HD8; HDAC 8; Hdac8; HDAC8; HDACL 1; HDACL1; Histone deacetylase 8; Histone deacetylase like 1; MRXS6; RPD 3; RPD3; WTS

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Stem Cells

• Purification :

  Affinity purification

• Concentration :

  0.7 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  42kDa

• Citation 01 :

  https://www.nature.com/articles/s41419-022-04901-x

• Isotype :

  IgG