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CAV1 Polyclonal Antibody

CAT: 0763-E-AB-30778-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-30778-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity) . Involved in the costimulatory signal essential for T-cell receptor (TCR) -mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Abbreviation
Caveolin-1
UniProt
Q03135
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Caveolin-1
Target
BSCL3; CAV; CAV1; CAV1; caveolae protein;22 kD; caveolin 1 alpha isoform; caveolin 1 beta isoform; Caveolin 1 caveolae protein 22kDa; Caveolin-1; Caveolin1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; OTTHUMP00000025031; PPH3; VIP 21; VIP21
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction; Tags and Cell Markers
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC 1:50-300; IF 1:50-300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
20kDa
Observed Molecular Weight
25kDa
Isotype
IgG

UniProtKB · Q03135

Caveolin-1

CAV1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q03135
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CAV1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9UGP1, Q9UNG1, Q9UQH6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiation

Cellular component

Cell membraneCytoplasmGolgi apparatusMembrane

Disease

Congenital generalized lipodystrophyDiabetes mellitusDisease variant

Biological process

Host-virus interaction

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