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STAT3 Monoclonal Antibody

CAT: 0763-E-AB-22166-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-22166-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214) .
Abbreviation
STAT3
UniProt
P40763
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein
Target
1110034C02Rik; Acute Phase Response Factor; Acute-phase response factor; ADMIO; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3 (acute phase response factor) ; Signal transducer and activator of transcription 3; STAT 3; Stat3; STAT3
Clonality
Monoclonal
Clone
3F4
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Developmental Biology; Signal Transduction; Stem Cells
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000; IHC 1:100-200
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
79,86kDa
Isotype
IgG

UniProtKB · P40763

Signal transducer and activator of transcription 3

STAT3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P40763
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
STAT3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K7B8, K7ENL3, O14916, Q9BW54
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Disease

Diabetes mellitusDisease variantDwarfism

Biological process

Host-virus interactionTranscriptionTranscription regulation

Domain

SH2 domain

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