CD2 Monoclonal Antibody

CAT: 0763-E-AB-22097-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-22097-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene.CD2 (CD2 Molecule) is a Protein Coding gene. Diseases associated with CD2 include Penis Squamous Cell Carcinoma and Immune Defect Due To Absence Of Thymus. Among its related pathways are PEDF Induced Signaling and TGF-Beta Pathway. GO annotations related to this gene include protein homodimerization activity and receptor activity.

Abbreviation

CD2

UniProt

P06729

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide

Target

CD 2; CD2; CD2 antigen (p50) ; sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor; Ly-37; Lymphocyte function antigen 2; lymphocyte-function antigen-2; OTTHUMP00000024366; Rosette receptor; Sheep erythrocyte receptor; SRBC; T cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-lymphocyte surface CD2 antigen; T11

Clonality

Monoclonal

Clone

Clone:4C3

Conjugation

Unconjugated

Applications

IHC-p

Field of Research

Cancer; Immunology; Stem Cells

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

IHC 1:50-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P06729

T-cell surface antigen CD2

CD2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P06729
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CD2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q96TE5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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