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Phospho-STAT2 (Tyr690) Polyclonal Antibody

CAT: 0763-E-AB-21152-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-21152-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STA
Abbreviation
Stat2 (phospho Tyr690)
UniProt
P52630
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human Stat2 around the phosphorylation site of Tyr690
Target
Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator; ISGF 3; ISGF3; MGC59816; P113; signal transducer and activator of transcription 2 113kD; Signal transducer and activator of transcription 2; STAT113; Stat2; STAT2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
98kDa
Observed Molecular Weight
113kDa
Isotype
IgG

UniProtKB · P52630

Signal transducer and activator of transcription 2

STAT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52630
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
STAT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DLC7, G3V2M6, Q16430, Q16431, Q9UDL4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseHost-virus interactionTranscriptionTranscription regulation

Cellular component

CytoplasmNucleus

Disease

Disease variant

PTM

PhosphoproteinUbl conjugation

Domain

SH2 domain

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