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FAM111B Polyclonal Antibody

CAT: 0763-E-AB-19841-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19841-01Size:20 µL
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Background
This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP) . Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐ like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.
Abbreviation
FAM111B
UniProt
Q6SJ93
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human FAM111B
Target
Cancer associated nucleoprotein; CANP ; Protein FAM111B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
1.5 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q6SJ93

Serine protease FAM111B

F111B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6SJ93
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FAM111B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.-
Processing
—
Secondary accessions
B4E2G2, Q6P661
Protein keywords

PTM

AcetylationIsopeptide bondUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Molecular function

HydrolaseProtease

Technical term

Proteomics identificationReference proteome

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