Products for Research Use Only
RegisterLogin

CORO2B Polyclonal Antibody

CAT: 0763-E-AB-19746-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-19746-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Coronins are a family of WD repeat-containing, actin-binding proteins that localize to submembraneous areas and regulate cell motility and cytoskeletal rearrangement. Coronin 1A (CORO1A, CLIPINA, CLABP, TACO, p57) can form coiled coil-mediated homotrimeric complexes that influence early phagosome formation. PKC-dependent phosphorylation of Coronin 1B (CORO1B) at Serine 2 regulates leading edge dynamics and cell motility in fibroblasts through interactions with Arp2/3 complex. Coronin 1C (CORO1C, Coronin 3, HCRNN4) is abundant in differentiating Neuro-2a cells, PC-12 cells and primary oligodendrocytes, where it is thought to influence neuron morphogenesis and migration. Coronin 2A (CORO2A, CLIPINB, IR10, WDR2) is a component of the approximately 1.5-2 megadalton N-CoR (nuclear receptor corepressor) complex of 10-12 proteins, which recruits HDACs to generate repressive chromatin. Coronin 7 (CORO7, CRN7) localizes to the Golgi membrane and influences the organization of intracellular membrane compartments and vesicular trafficking. Coronin 2B (CORO2B, CLIPINC) and Coronin 6 (CORO6) are similar to other members of this family, since they possess a conserved basic N-terminal motif and 3-10 WD repeats clustered in one to two core domains.
Abbreviation
CORO2B
UniProt
Q9UQ03
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human CORO2B
Target
Actin binding protein; Clipin-C; CLIPINC; COR2B; CORO2B; Coronin actin binding protein 2B; Coronin; Coronin-2B; Coronin-like protein C; Protein FC96
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
1.5 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

Related Products

CatalogName
E-AB-65046-01CORO1B Polyclonal Antibody
E-AB-52651-01CORO2A Polyclonal Antibody
E-AB-90858-01CORO2A Polyclonal Antibody
E-AB-18735-01CORO2A Polyclonal Antibody
E-AB-17844-01CORO2A Polyclonal Antibody
E-AB-19721-01CORO1B Polyclonal Antibody
E-AB-14887-01CORO1C Polyclonal Antibody
E-AB-11096-01CORO1C Polyclonal Antibody
E-AB-68427-01CORO1A Polyclonal Antibody
E-AB-65139-01Polyclonal AntibodyPC1 Polyclonal Antibody

Alternative Products

CatalogName
MBS9234947-01CORO2B Polyclonal Antibody
TA372324CORO2B Rabbit Polyclonal Antibody
TMAB-04589-01Anti-CORO2B Polyclonal Antibody

Popular Products