PRPF8 Polyclonal Antibody

• Background:

  Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

• Abbreviation:

  PRPF8

• UniProt:

  Q6P2Q9

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human PRPF8

• Target:

  220 kDa U5 snRNP specific protein;220 kDa U5 snRNP-specific protein; Apoptosis regulated protein 1; Apoptosis regulated protein 2; HPRP8; p220; Pre mRNA processing factor 8; Pre mRNA-processing factor 8; S. cerevisiae; homolog of; Pre-mRNA-processing-splicing factor 8; Precursor mRNA processing protein ; PRP8; PRP8 homolog; PRP8 pre mRNA processing factor 8 homolog ; PRP8; PRPC8; Prpf8; Retinitis pigmentosa 13 (autosomal dominant) ; RP13; SNRNP220; Splicing factor Prp8; U5 snRNP specific protein ; U5 snRNP specific protein (220 kD) ; ortholog of S. cerevisiae Prp8p

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Neuroscience

• Purification:

  Antigen affinity purification

• Concentration:

  0.6 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  274 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG