CAPN9 Polyclonal Antibody

CAT: 0763-E-AB-19659-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-19659-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.CAPN9 (Calpain 9) is a Protein Coding gene. Diseases associated with CAPN9 include Gastric Cancer. Among its related pathways are Degradation of the extracellular matrix and Arrhythmogenic right ventricular cardiomyopathy (ARVC) . GO annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPN3.
Abbreviation
CAPN9
UniProt
O14815
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human CAPN9
Target
Calpain-9; Calpain9; CAN9; CAPN 9; CAPN9; CG36 protein; Digestive tract specific calpain; Digestive tract-specific calpain; GC36; nCL-4; nCL4; New calpain 4; novel calpain large subunit-4; novel calpain large subunit4; OTTHUMP00000035899; OTTHUMP00000035900; Protein CG36
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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