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ZIC1 Polyclonal Antibody

CAT: 0763-E-AB-19554-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19554-01Size:20 µL
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Background
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.
Abbreviation
ZIC1
UniProt
Q15915
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ZIC1
Target
Odd paired homolog Drosophila; Zic 1; ZIC; Zic family member 1 (odd-paired Drosophila homolog) ; Zic family member 1; Zic protein member 1; zic1; ZIC1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1; Zinc finger protein ZIC1; ZNF 201; ZNF201
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.6 mg/mL
Dilution
IHC 1:40-1:250
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q15915

Zinc finger protein ZIC 1

ZIC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15915
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ZIC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q2M3N1
Protein keywords

Molecular function

ActivatorDevelopmental proteinDNA-binding

Disease

CraniosynostosisDisease variantIntellectual disability

Cellular component

CytoplasmNucleus

Biological process

DifferentiationNeurogenesisTranscriptionTranscription regulation

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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