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SERPINH1 Polyclonal Antibody

CAT: 0763-E-AB-19472-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19472-01Size:20 µL
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Background
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
Abbreviation
SERPINH1
UniProt
P50454
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human SERPINH1
Target
47 kDa heat shock protein;47 kDa heat shock protein precursor; Arsenic transactivated protein 3; Arsenic-transactivated protein 3; AsTP 3; AsTP3; CBP 1; CBP 2; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; Collagen binding protein 1; Collagen binding protein 2; Collagen binding protein; Collagen-binding protein 2; Collagen-binding protein; Colligen; Colligin 1; Colligin 2; Colligin; colligin-1; colligin-2; gp46; Heat shock protein 47; Heat-shock protein 47; HGNC 1547; Hsp 47; J6; OI10; PIG 14; PIG14; PPROM; Proliferation inducing gene 14; Proliferation inducing gene 14 protein; RA A47; RA-A47; Rheumatoid arthritis antigen A 47; rheumatoid arthritis antigen A-47; Rheumatoid arthritis related antigen RA A47; Rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) proteinase inhibitor; clade H (heat shock protein 47) ; member 1; (collagen binding protein 1) ; serine (or cysteine) proteinase inhibitor; clade H (heat shock protein 47) ; member 2; (collagen-binding protein 2) ; Serine or cysteine proteinase inhibitor clade H member 1; Serine or cysteine proteinase inhibitor clade H member 2; SERPH; Serpin H1; Serpin peptidase inhibitor clade H member 1; serpin peptidase inhibitor; clade H (heat shock protein 47) ; member 1; (collagen binding protein 1) ; Serpin peptidase inhibitor; clade H; member 1; SERPINH1; SERPINH2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Signal transduction
Purification
Antigen affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · P50454

Serpin H1

SERPH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P50454
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B3KVJ3, P29043, Q5XPB4, Q6NSJ6, Q8IY96, Q9NP88
Protein keywords

PTM

AcetylationGlycoproteinPhosphoprotein

Molecular function

Chaperone

Cellular component

Endoplasmic reticulum

Disease

Osteogenesis imperfecta

Technical term

Proteomics identificationReference proteome

Domain

Signal

Biological process

Stress response