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TMED10 Polyclonal Antibody

CAT: 0763-E-AB-19178-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19178-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Abbreviation
TMED10
UniProt
P49755
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human TMED10
Target
1110014C03Rik ;21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein; MGC102351; p23; p24 family protein delta 1; p24 family protein delta-1; p24 (DELTA) ; p24delta; p24delta1; S31I125; S31III125; TMED 10; Tmed10; TMEDA; Tmp 21 I; Tmp 21; Tmp 21 I; Tmp-21-I; Transmembrane emp24 domain containing protein 10; Transmembrane emp24 domain-containing protein 10; Transmembrane emp24-like trafficking protein 10 (yeast) ; Transmembrane protein Tmp21; Transmembrane trafficking protein 21kD
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.14 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · P49755

Transmembrane emp24 domain-containing protein 10

TMEDA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49755
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TMED10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Protein TMED10
EC number
—
Processing
Precursor
Secondary accessions
A0A024R6I3, B2R605, B4DL12, G3V2K7, Q15602, Q16536, Q53GF9, Q86TC2, Q86TS5
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumGolgi apparatusMembrane

Technical term

Direct protein sequencingProteomics identificationReference proteome

Biological process

ER-Golgi transportProtein transportTransport

PTM

GlycoproteinMethylation

Domain

SignalTransmembraneTransmembrane helix

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