HLA-E Polyclonal Antibody

• Background:

  HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

• Abbreviation:

  HLA-E

• UniProt:

  P13747

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human HLA-E

• Target:

  HLA class I histocompatibility antigen E alpha chain; EA1.2; EA2.1; HLA 6.2; HLA class I histocompatibility antigen alpha chain E; HLA class I histocompatibility antigen E alpha chain precursor ; HLA class I histocompatibility antigen E alpha chain precursor; HLA6.2; HLAE; Lymphocyte antigen; Major histocompatibility complex class I E; MHC; MHC class I antigen E; MHC HLA E alpha 1; MHC HLA E alpha 2.1; QA1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Immunology

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG