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DUSP7 Polyclonal Antibody

CAT: 0763-E-AB-18976-04Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18976-04Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947) -like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]) .
Abbreviation
DUSP7
UniProt
Q16829
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human DUSP7
Target
Dual specificity phosphatase 7; Dual specificity protein phosphatase 7; Dual specificity protein phosphatase PYST2; DUS7; Dusp7; Jnk Stimulatory Phosphatase 1; JSP1; MAP kinase phosphatase X; MKPX; PYST2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.72 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q16829

Dual specificity protein phosphatase 7

DUS7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16829
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DUSP7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16, 3.1.3.48
Processing
—
Secondary accessions
Q2M3J7, Q8NFJ0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usage

Cellular component

Cytoplasm

Molecular function

HydrolaseProtein phosphatase