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ST8SIA4 Polyclonal Antibody

CAT: 0763-E-AB-18911-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18911-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
ST8SIA4
UniProt
Q92187
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human ST8SIA4
Target
8-sialyltransferase 8D;8-sialyltransferase; Alpha 2 8 sialyltransferase 8D; Alpha-2; CMP N acetylneuraminate poly alpha 2 8 sialyl transferase; CMP-N-acetylneuraminate-poly-alpha-2; Polysialyltransferase 1; Polysialyltransferase-1; PST; PST1; SIA8D; Sialyltransferase 8 alpha 2 8 polysialytransferase D ; Sialyltransferase 8D; Sialytransferase St8Sia IV; SIAT8-D; SIAT8D; ST8 alpha N acetyl neuraminide alpha 2 8 sialyltransferase 4; ST8Sia IV; ST8SIA4; ST8SiaIV
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags; Cell Markers
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
41 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q92187

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

SIA8D_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92187
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ST8SIA4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.3.-
Processing
—
Secondary accessions
A8KA07, G3V104, Q8N1F4, Q92693
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Molecular function

GlycosyltransferaseTransferase

Cellular component

Golgi apparatusMembraneSecreted

Domain

Signal-anchorTransmembraneTransmembrane helix

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