GTF2A2 Polyclonal Antibody

CAT: 0763-E-AB-18882-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-18882-01Size:20 µL
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AVAILABILITY: InStock
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Background
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972) . The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]) .
Abbreviation
GTF2A2
UniProt
P52657
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human GTF2A2
Target
General transcription factor IIA; General transcription factor IIA subunit 2; General transcription factor IIA; 2 (12kD subunit) ; General transcription factor IIA; 2; 12kDa; gtf2a2; HsT18745; T2AG; TF2A2; TFIIA 12; TFIIA; TFIIA gamma ; TFIIA p12 subunit; TFIIA-12; TFIIA-gamma; TFIIA12; TFIIAS; Transcription initiation factor IIA gamma chain; Transcription initiation factor IIA subunit 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.54 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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