GARS Polyclonal Antibody

• Background:

  This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  GARS

• UniProt:

  P41250

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human GARS

• Target:

  AP 4 A synthetase; Charcot Marie Tooth neuropathy 2D; Charcot Marie Tooth neuropathy neuronal type D; CMT2D ; Diadenosine tetraphosphate synthetase; DSMAV ; EC 6.1.1.14; Glycine tRNA ligase; Glycyl tRNA synthetase; GlyRS ; HMN5; SMAD1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling

• Purification:

  Antigen affinity purification

• Concentration:

  0.6 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  83 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG