CA11 Polyclonal Antibody

• Background :

  Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.

• Abbreviation :

  CA11

• UniProt :

  O75493

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Fusion protein of human CA11

• Target :

  CA-RP II; CA-RP XI; CA-XI; CA11; CAH11; Carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; CARP XI; CARP-2; CARP2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Cell Biology

• Purification :

  Antigen affinity purification

• Concentration :

  0.7 mg/mL

• Dilution :

  IHC 1:40-1:200

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG