BDNF Polyclonal Antibody

• Background:

  BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. It play a role in the regulation of stress response and in the biology of mood disorders.

• Abbreviation:

  BDNF

• UniProt:

  P23560

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Fusion protein of human BDNF

• Target:

  Abrineurin; ANON2; BDNF; BDNF; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; BULN2; MGC34632; Neurotrophin

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cardiovascular; Metabolism; Neuroscience

• Purification:

  Antigen affinity purification

• Concentration:

  1.14 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:100

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  28 kDa

• Observed Molecular Weight:

  Refer to figures

• Citation 01:

  https://pubs.rsc.org/en/content/articlelanding/2022/fo/d2fo00423b

• Citation 02:

  https://link.springer.com/article/10.1007/s12035-022-03026-8

• Citation 03:

  https://www.hindawi.com/journals/omcl/2018/4572893/abs/

• Citation 04:

  https://pubs.acs.org/doi/abs/10.1021/acschemneuro.1c00648

• Citation 05:

  https://link.springer.com/article/10.1007/s00213-021-05996-4

• Citation 06:

  https://link.springer.com/article/10.1007/s12640-021-00467-2

• Citation 07:

  https://www.liebertpub.com/doi/abs/10.1089/jmf.2021.0154

• Isotype:

  IgG