HDAC1 Polyclonal Antibody

• Background :

  Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

• Abbreviation :

  HDAC1

• UniProt :

  Q13547

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Fusion protein of human HDAC1

• Target :

  DKFZp686H12203; GON 10; HD1; HDAC 1; HDAC1; HDAC1; Histone deacetylase 1; Reduced potassium dependency yeast homolog like 1; RPD3; RPD3L1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Stem Cells

• Purification :

  Antigen affinity purification

• Concentration :

  1.02 mg/mL

• Dilution :

  WB 1:1000-1:5000; IHC 1:50-1:200

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  55 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG