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RASA3 Polyclonal Antibody

CAT: 0763-E-AB-16753-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16753-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2.
Abbreviation
RASA3
UniProt
Q14644
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human RASA3
Target
GAP III; GAP1 (IP4BP) ; GAP1IP4BP; GAPIII; GTPase activating protein 1 family; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins P4-binding protein; Ins (1 3 4 5) P4 binding protein; Ins (1345) P4 binding protein; MGC46517; MGC47588; Ras GTPase activating protein 3; Ras GTPase-activating protein 3; RAS p21 protein activator 3; RASA 3; RASA3; RASA3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q14644

Ras GTPase-activating protein 3

RASA3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14644
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RASA3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NL15, F8W6X8, Q8IUY2
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Molecular function

GTPase activation

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger