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CD38 Polyclonal Antibody

CAT: 0763-E-AB-16317-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16317-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion, signal transduction and calcium signaling. Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Abbreviation
CD38
UniProt
P28907
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human CD38
Target
Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase 1; ADP ribosyl cyclase; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; ADP-ribosyl cyclase 1; ADPRC 1; ADPRC1; cADPr hydrolase 1; CD 38; CD38; CD38 antigen (p45) ; CD38 antigen; CD38 molecule; Cd38-rs1; CD38; CD38H; Cyclic ADP ribose hydrolase; Cyclic ADP ribose hydrolase 1; Cyclic ADP-ribose hydrolase 1; EC 3.2.2.5; Ecto nicotinamide adenine dinucleotide glycohydrolase; I-19; I19 (mouse) ; Lymphocyte differentiation antigen CD38; NAD (+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse) ; OTTHUMP00000158633; OTTHUMP00000217743; p45; T10
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Immunology; Stem cells
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Isotype
IgG

UniProtKB · P28907

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

CD38_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P28907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD38
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.2.2.-, 3.2.2.6
Processing
—
Secondary accessions
O00121, O00122, Q96HY4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoprotein

Molecular function

HydrolaseReceptorTransferase

Ligand

NADNADP

Domain

Signal-anchorTransmembraneTransmembrane helix

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