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AP1B1 Polyclonal Antibody

CAT: 0763-E-AB-16161-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16161-02Size:60 µL
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Background
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Abbreviation
AP1B1
UniProt
Q10567
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human AP1B1
Target
ADTB1; BAM22; AP105A; CLAPB2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q10567

AP-1 complex subunit beta-1

AP1B1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q10567
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AP1B1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
C9JRD1, F8WDL0, P78436, Q20WL3, Q86X54
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationNitration

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasmic vesicleGolgi apparatusMembrane

Disease

DeafnessDisease variantIchthyosis

Biological process

Protein transportTransport

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