MMP17 Polyclonal Antibody

• Background:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

• Abbreviation:

  MMP17

• UniProt:

  Q9ULZ9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human MMP17

• Target:

  Matrix metalloproteinase 17; Matrix metalloproteinase 17 membrane inserted; Matrix metalloproteinase-17; Membrane type 4 matrix metalloproteinase; Membrane type matrix metalloproteinase 4; Membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP 17; MMP-17; Mmp17; MMP17; MT MMP 4; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP 4; MTMMP4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cell Biology; Cardiovascular; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.3 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58kDa

• Isotype:

  IgG