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MMP17 Polyclonal Antibody

CAT: 0866-RD89535A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89535A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers.
Description
This is a MMP17 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MMP17, MMP-17, MT4-MMP, MT4MMP, MTMMP4
Gene ID
4326
Swiss Prot
Q9ULZ9
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MMP17
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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