Products for Research Use Only

NECTIN4 Polyclonal Antibody

CAT: 0763-E-AB-15250-02Size: 60 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-15250-02Size:60 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients.
Abbreviation
PVRL4
UniProt
Q96NY8
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human PVRL4
Target
DKFZp686K05193; EDSS1; Ig superfamily receptor LNIR; Nectin 4; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; PRR4; pvrl4; PVRL4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96NY8

Nectin-4

NECT4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96NY8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NECTIN4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DQW3, Q96K15
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell junctionCell membraneMembraneSecreted

Disease

Disease variantEctodermal dysplasia

PTM

Disulfide bondGlycoprotein

Molecular function

Host cell receptor for virus entryReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix