NECTIN4 Polyclonal Antibody

• Background:

  This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

• Description:

  This is a NECTIN4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DKFZp686K05193, EDSS1, Ig superfamily receptor LNIR, Nectin 4, Nectin-4, poliovirus receptor-related 4, Processed poliovirus receptor-related protein 4, PRR4, pvrl4, PVRL4

• Swiss Prot:

  Q96NY8

• Accession Number:

  BC010423

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human PVRL4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  55 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG