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BMX Polyclonal Antibody

CAT: 0763-E-AB-15000-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15000-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, whicHuman, Mouseediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Abbreviation
BMX
UniProt
P51813
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human BMX
Target
Bmx; BMX non receptor tyrosine kinase; BMX; BONE MARROW KINASE; X-LINKED; Bone marrow tyrosine kinase gene in chromosome X protein; Cytoplasmic tyrosine protein kinase BMX; Cytoplasmic tyrosine-protein kinase BMX; Epithelial and endothelial tyrosine kinase; ETK; NKT38; NTK 38; NTK38; Protein tyrosine kinase BMX; PSCTK 2; PSCTK 3; PSCTK2; PSCTK3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P51813

Cytoplasmic tyrosine-protein kinase BMX

BMX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51813
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BMX
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
A6NIH9, O60564, Q12871
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ApoptosisCell adhesionStress response

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Cellular component

Cytoplasm

Molecular function

KinaseTransferaseTyrosine-protein kinase

PTM

Phosphoprotein

Domain

SH2 domainZinc-finger

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