EIF3H Polyclonal Antibody

CAT: 0763-E-AB-14979-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-14979-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Abbreviation

EIF3H

UniProt

O15372

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant protein of human EIF3H

Target

EIF-3-gamma; eIF3 gamma; eIF3 p40; eIF3 p40 subunit; eIF3h; EIF3H; EIF3S3; Eukaryotic translation initiation factor 3 subunit 3; Eukaryotic translation initiation factor 3 subunit H; MGC102958

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

0.8 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

40kDa

Isotype

IgG

UniProtKB · O15372

Eukaryotic translation initiation factor 3 subunit H

EIF3H_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O15372
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF3H
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF3h
EC number: —
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cytoplasm

Molecular function

Initiation factor

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Biological process

Protein biosynthesis

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Alternative Products

Catalog	Name
MBS2525805-01	EIF3H Polyclonal Antibody
MBS9464835-01	EIF3H Rabbit Polyclonal Antibody