EDA2R Polyclonal Antibody

• Background:

  EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

• Abbreviation:

  EDA2R

• UniProt:

  Q9HAV5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human EDA2R

• Target:

  9430060M22Rik; Ectodysplasin A2 isoform receptor; Ectodysplasin A2 receptor; EDA A2R; EDA-A2 receptor; EDA2R; EDAA2R; MGC124099; OTTMUSP00000019574; OTTMUSP00000019575; RP23-188N15.1; TNFRSF27; TNR27; Tumor necrosis factor receptor superfamily member 27; Tumor necrosis factor receptor superfamily member XEDAR; X linked ectodysplasin A2 receptor; X linked ectodysplasin receptor; X-linked ectodysplasin-A2 receptor; XEDAR

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Signal Transduction; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:200-1:1000; IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33kDa

• Isotype:

  IgG