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Cytochrome b5 Polyclonal Antibody

CAT: 0763-E-AB-14924-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-14924-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CYB5A
UniProt
P00167
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human CYB5A
Target
CYB 5; CYB 5A; CYB5; CYB5; Cyb5a; Cytochrome b 5; Cytochrome b5 (microsomal) ; Cytochrome b5; Cytochrome b5 type A (microsomal) ; Cytochrome b5 type A; MCB 5; MCB5; Microsomal cytochrome b5; Microsomal cytochrome b5 type A; Type 1 cyt b5
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa
Isotype
IgG

UniProtKB · P00167

Cytochrome b5

CYB5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00167
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYB5A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8MV91, F8WEU4, Q6IB14
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulumMembraneMicrosome

Disease

Disease variant

Biological process

Electron transportTransport

Ligand

HemeIronMetal-binding

Domain

TransmembraneTransmembrane helix

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