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PAK2 Polyclonal Antibody

CAT: 0763-E-AB-14278-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-14278-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Abbreviation
PAK2
UniProt
Q13177
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human PAK2
Target
C-t-PAK2; CB422; EC 2.7.11.1; Gamma PAK; Gamma-PAK; hPAK65; Kinase; p21 (CDKN1A) activated kinase 2; p21 (CDKN1A) -activated kinase 2a; p21 activated kinase 2; p21 protein (Cdc42/Rac) -activated kinase 2; p21 protein Cdc42 Rac activated kinase 2; p21-activated kinase 2; p21-activated kinase;65-KD; p21-activated protein kinase I; p21CDKN1A activated kinase 2; p27; p34; p58; p65PAK; PAK 2; PAK-2; PAK-2p34; Pak2; PAK2; PAK65; PAKgamma; S6 H4 kinase; S6/H4 kinase; Serine threonine protein kinase PAK 2; Serine/threonine protein kinase PAK 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cell Biology; Microbiology; Signal Transduction
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:200-1:1000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
58kDa
Isotype
IgG

UniProtKB · Q13177

Serine/threonine-protein kinase PAK 2

PAK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13177
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q13154, Q6ISC3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationLipoproteinMyristatePhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeKinaseSerine/threonine-protein kinaseTransferase

Biological process

ApoptosisGrowth regulationHost-virus interaction

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmMembraneNucleus

Disease

Disease variant

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